Tehran University of Medical Sciences
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Abdolhosein Rouholamini najafabadi

Contact Information
Tel: 00982164122211
Fax: 00982166959057
Academic Rank
Assistant Professor
School
Pharmacy
Pharmaceutics
About
CV last edited on: 2015/07/02

Papers

English

1.

Optimization of a spray drying process to prepare dry powder microparticles containing plasmid nanocomplex


Authors: Mohajel, N., Najafabadi, A.R., Azadmanesh, K., Vatanara, A., Moazeni, E., Rahimi, A., Gilani, K.
International Journal of Pharmaceutics, Vol.423, No.2, Year. 2012, Page:577-585,
2.

Stability studies of chitosan-DNA-FAP-B nanoparticles for gene delivery to lung epithelial cells


Authors: Mohammadi, Z., Dorkoosh, F.A., Hosseinkhani, S., Amini, T., Rahimi, A.A., Najafabadi, A.R., Tehrani, M.R
Acta Pharmaceutica, Vol.62, No.1, Year. 2012, Page:83-92,
3.

Loading hydrophilic drug in solid lipid media as nanoparticles: Statistical modeling of entrapment efficiency and particle size


Authors: Ghadiri, M., Fatemi, S., Vatanara, A., Doroud, D., Najafabadi, A.R., Darabi, M., Rahimi, A.A.
International Journal of Pharmaceutics, Vol.424, No.1-2, Year. 2012, Page:128-137,
4.

Design, modeling, and expression of erythropoietin cysteine analogs in Pichia pastoris: Improvement of mean residence times and in vivo activities through cysteine-specific PEGylation


Authors: Maleki, A., Madadkar-Sobhani, A., Roohvand, F., Najafabadi, A.R., Shafiee, A., Khanahmad, H., Cohan, R.A., Namvar, N., Tajerzadeh, H.
European Journal of Pharmaceutics and Biopharmaceutics, Vol.80, No.3, Year. 2012, Page:499-507,
5.

Development of chitosan-based nanoparticles for pulmonary delivery of itraconazole as dry powder formulation


Authors: Jafarinejad, S., Gilani, K., Moazeni, E., Ghazi-Khansari, M., Najafabadi, A.R., Mohajel, N.
Powder Technology, Vol.222, Year. 2012, Page:65-70,
6.

Production of ultrafine drug particles through rapid expansion of supercritical solution; a statistical approach


Authors: Pourasghar, M., Fatemi, S., Vatanara, A., Rouholamini Najafabadi, A.
Powder Technology, Vol.225, Year. 2012, Page:21-26,
7.

Screening and evaluation of variables in the formation of antibody particles by spray drying


Authors: Ramezani, V., Vatanara, A., Najafabadi, A.R., Gilani, K., Nabi-Meybodi, M
Powder Technology , Year. 2012,
8.

Effects of processing parameters on particle size of ultrasound prepared chitosan nanoparticles: An Artificial Neural Networks Study


Authors: Esmaeilzadeh-Gharedaghi, E., Faramarzi, M.A., Amini, M.A., Rouholamini Najafabadi, A., Rezayat, S.M., Amani, A.
Pharmaceutical Development and Technology , Vol.17, No.5, Year. 2012, Page:638 - 647,
9.

Process variables in the formation of nanoparticles of megestrol acetate through rapid expansion of supercritical CO2


Authors: Samei, M., Vatanara, A., Fatemi, S., Rouholamini Najafabadi, A.
Journal of Supercritical Fluids, Vol.70, Year. 2012, Page:1-7,
10.

Paromomycin Loaded Solid Lipid Nanoparticles: Characterization of Production Parameters ))


Authors: Ghadiri, M., Vatanara, A., Doroud, D., Fatemi, S., Rouholamini Najafabadi, A.
Biotechnology and Bioprocess Engineering, Vol.16, Year. 2011, Page:617-623,
11.

Pharmacokinetic study of niosome-loaded insulin in diabetic rats


Authors: Pardakhty, A., Moazeni, E., Varshosaz, J., Hajhashemi, V., Rouholamini Najafabadi, A.
DARU, Journal of Pharmaceutical Sciences, Vol.19, No.6, Year. 2011, Page:404-411,
12.

In vivo transfection study of chitosan-DNA-FAP-B nanoparticles as a new non viral vector for gene delivery to the lung.


Authors: Mohammadi Z, Dorkoosh FA, Hosseinkhani S, Gilani K, Amini T, Najafabadi AR, Tehrani MR.
Int J Pharm, Vol.421, No.1, Year. 2011, Page:183-188,
13.

Preparation and evaluation of chitosan-DNA-FAP-B nanoparticles as a novel non-viral vector for gene delivery to the lung epithelial cells


Authors: Mohammadi, Z., Abolhassani, M., Dorkoosh, F.A., Hosseinkhani, S., Gilani, K., Amini, T., Najafabadi, A.R., Tehrani, M.R.
International Journal of Pharmaceutics, Vol.409, No.1-2, Year. 2011, Page:307-313,
14.

Evaluation of bioactivity and pharmacokinetic characteristics of PEGylated P.pastoris-expressed erythropoietin.


Authors: Maleki A, Najafabadi AR, Roohvand F, Shafiee A, Khanahmad H, Faghihi H, Hedayati MH, Tajerzadeh H.
Drug Deliv, Vol. 2011 18(8):570-7. Epub 2011 Sep, No.8, Year. 2011,
15.

Delivery of a cocktail DNA vaccine encoding cysteine proteinases type I, II and III with solid lipid nanoparticles potentiate protective immunity against Leishmania major infection


Authors: Doroud, D., Zahedifard,F., Vatanara,A., Rouholamini Najafabadi,A., Taslimi,., Vahabpour,R., Torkashvand,F., Vaziri,B. Rafati,S
Journal of Controlled Release, Year. 2011,
16.

Entrapment of 5-fluorouracil into PLGA matrices using supercritical antisolvent processes


Authors: Kalantarian, P., Haririan, I., Najafabadi, A.R., Shokrgozar, M.A., Vatanara A.
J. Pharm. Pharmacol, Vol.63, No.4, Year. 2011, Page:500-506,
17.

C-terminal domain deletion enhances the protective activity of cpa/cpb loaded solid lipid nanoparticles against Leishmania major in BALB/c mice


Authors: Doroud D, Zahedifard F, Vatanara A, Taslimi Y, Vahabpour R, Torkashvand F, Vaziri B, Najafabadi A.R. Rafati S
PLoS Neglected Tropical Diseases., Year. 2011,
18.

Cysteine proteinase type I, encapsulated in Solid Lipid Nanoparticles induces substantial protection against L.major infection in C57BL/6 mice


Authors: . Doroud, D., Zahedifard,F., Vatanara,A., Rouholamini Najafabadi,A.,
Journal of Controlled Release, Year. 2011,
19.

Cysteine proteinase type I, encapsulated in solid lipid nanoparticles induces substantial protection against Leishmania major infection in C57BL/6 mice


Authors: Doroud, D., Zahedifard, F., Vatanara, A., Najafabadi, A.R., Rafati, S.
Parasite Immunology, Vol.33, No.6, Year. 2011, Page:335-348,
20.

The effect of process parameters on the size and morphology of poly(D, L-Lactide-Co-Glycolide) micro/nanoparticles prepared by an oil in oil emulsion/solvent evaporation technique


Authors: Mahdavi, H., Mirzadeh, H., Hamishehkar, H., Jamshidi, A., Fakhari, A., Emami, J., Najafabadi, A.R., Gilani, K., Minaiyan, M., Najafi, M., Tajarod, M., Nokhodchi, A.
Journal of Applied Polymer Science, Vol.116, No.1, Year. 2010, Page:528-534,
21.

Effect of carrier morphology and surface characteristics on the development of respirable PLGA microcapsules for sustained-release pulmonary delivery of insulin


Authors: Hamishehkar, H., Emami, J., Najafabadi, A.R., Gilani, K., Minaiyan, M., Mahdavi, H., Nokhodchi, A
nternational Journal of Pharmaceutics, Vol.389, No.1-2, Year. 2010, Page:74-85,
22.

Pharmacokinetics and pharmacodynamics of controlled release insulin loaded PLGA microcapsules using dry powder inhaler in diabetic rats


Authors: Hamishehkar, H., Emami, J., Najafabadi, A.R., Gilani, K., Minaiyan, M., Hassanzadeh, K., Mahdavi, H., Koohsoltani, M., Nokhodchig, A
Biopharmaceutics and Drug Disposition, Vol.31, No. (2-3, Year. 2010, Page:189-201,
23.

Formulation and in vitro evaluation of ciprofloxacin containing niosomes for pulmonary delivery


Authors: Moazeni, E., Gilani, K., Sotoudegan, F., Pardakhty, A., Najafabadi, A.R., Ghalandari, R., Fazeli, M.R., amalifar, H
Journal of Microencapsulation,, Vol.27, No.7, Year. 2010, Page: 618-627. ,
24.

Cationic solid lipid nanoparticles loaded by cysteine proteinase genes as a novel anti-leishmaniasis DNA vaccine delivery system: Characterization and in vitro evaluations


Authors: Doroud, D., Vatanara, A., Zahedifard, F., Gholami, E., Vahabpour, R., Najafabadi, A.R., Rafati, S
Journal of Pharmacy and Pharmaceutical Sciences, Vol.13, No.3, Year. 2010, Page:320-335,
25.

Preparation of 5-fluorouracil nanoparticles by supercritical antisolvents for pulmonary delivery


Authors: Kalantarian, P., Najafabadi A.R., Haririan I., Vatanara A., Yamini Y., Darabi M., Gilani K
Int J Nanomedicine, Vol.5, Year. 2010, Page:763-770,
26.

Influence of carrier particle size, carrier ratio and addition of fine ternary particles on the dry powder inhalation performance of insulin-loaded PLGA microcapsules


Authors: Hamishehkar, H., Emami, J., Najafabadi, A.R., Gilani, K., Minaiyan, M., Mahdavi, H., Nokhodchi, A.
Powder Technology, Vol.201, No.3, Year. 2010, Page:289–295,
27.

Precipitation of fluticasone propionate microparticles using supercritical antisolvent


Authors: Vatanara, A., Rouholamini, N.A., Gilani, K., Asgharian, R., Darabi, M., Rafiee-Tehrani, M.
Daru, Vol.17, No.1, Year. 2009, Page:6-12,
28.

Particle size design of PLGA microspheres for potential pulmonary drug delivery using response surface methodology


Authors: Emami, J., Hamishehkar, H., Najafabadi, A.R., Gilani, K., Minaiyan, M., Mahdavi, H., Mirzadeh, H., Fakhari, A., Nokhodchi, A.
Journal of Microencapsulation, Vol.26, No.1, Year. 2009, Page:1-8,
29.

An efficient biosurfactant-producing bacterium Pseudomonas aeruginosa MR01, isolated from oil excavation areas in south of Iran


Authors: Lotfabad, T.B., Shourian, M., Roostaazad, R., Najafabadi, A.R., Adelzadeh, M.R., Noghabi, K.A
Colloids and Surfaces B: Biointerfaces, Vol.69, No.2, Year. 2009, Page:183-193,
30.

A novel approach to prepare insulin-loaded poly (lactic-co-glycolic acid) microcapsules and the protein stability study


Authors: .Emami, J., Hamishehkar, H., Najafabadi, A.R., Gilani, K., Minaiyan, M., Mahdavi, H., Nokhodchi, A
Journal of Pharmaceutical Sciences, Vol.98, No.5, Year. 2009, Page:1712-1731,
31.

Supercritical CO2 and highly selective aromatase inhibitors: Experimental solubility and empirical data correlation


Authors: Hojjati, M., Vatanara, A., Yamini, Y., Moradi, M., Najafabadi, A.R
Journal of Supercritical Fluids, Vol.50, No.3, Year. 2009, Page:203-209,
32.

Enrichment of omega3 fatty acids from Tyulka oil by supercritical CO2 extraction


Authors: Zakizadeh Nei Nei, H ., Fatemi, S.H., Salimi, A. R., Vatanara,A., Rouholamini Najafabadi, A
Enrichment of omega3 fatty acids from Tyulka oil by supercritical CO2 extraction , Year. 2009,
33.

The effect of formulation variables on the characteristics of insulin-loaded poly(lactic-co-glycolic acid) microspheres prepared by a single phase oil in oil solvent evaporation method


Authors: Hamishehkar, H., Emami, J., Najafabadi, A.R., Gilani, K., Minaiyan, M., Mahdavi, H., Nokhodchi, A
Colloids and Surfaces B: Biointerfaces, Vol.47, No.1, Year. 2009, Page:340-349,
34.

Enrichment of omega3 fatty acids from Tyulka oil by supercritical CO 2 extraction


Authors: Nei, H.Z.N., Fatemi, Sh., Salimi, A.R., Vatanara, A., Najafabadi, A.R
Journal of Chemical Technology and Biotechnology, Vol.48, No.12, Year. 2009, Page:1854-1859,
35.

Comparison of super critical fluid extraction and hydrodistillation methods on Lavander's essential oil composition and yield


Authors: Rezazadeh, Sh., Baha-Aldini, B.Z.B.F., Vatanara, A., Behbahani, B., Rouholamini Najafabadi, A., Maleky-Doozzadeh, M., Yarigar-Ravesh, M., Pirali Hamedani, M
Journal of Medicinal Plants, Vol.7, No.4, Year. 2008, Page:63-68,
36.

The effect of spray drying solvent on in vitro deposition profiles and pulmonary absorption of rifampicin microparticles


Authors: Darbandi, M., Gilani, K., Rouholamini Najafabadi, A., Barghi, M., Tajerzadeh, H.
Journal of Drug Delivery Science and Technology, Vol.18, No.3, Year. 2008, Page:203-208,
37.

The effect of vehicles on spray drying of rifampicin inhalable microparticles: In vitro and in vivo evaluation


Authors: Darbandi, M.A., Rouholamini, N.A., Gilani, K., Tajerzadeh, H.
Daru, Vol.16, No.3, Year. 2008, Page:128-135,
38.

Comparison of super critical fluid extraction and hydrodistillation methods on Lavander's essential oil composition and yield


Authors: Rezazadeh, Sh., Baha-Aldini, B.Z.B.F., Vatanara, A., Behbahani, B., Rouholamini Najafabadi, A., Maleky-Doozzadeh, M., Yarigar-Ravesh, M., Pirali Hamedani, M
Journal of Medicinal Plants, Vol.7, No.4, Year. 2008, Page: 63-68,
39.

Characterization and aerodynamic evaluation of spray dried recombinant human growth hormone using protein stabilizing agents


Authors: Jalalipour, M., Gilani, K., Tajerzadeh, H., Najafabadi, A.R., Barghi, M.
International Journal of Pharmaceutics, Vol.352, No.1-2, Year. 2008, Page: 209-216,
40.

Comparative approach for detection of biosurfactant-producing bacteria isolated from Ahvaz petroleum excavation areas in south of Iran


Authors: Afshar, S., Lotfabad, T.B., Roostaazad, R., Najafabadi, A.R., Noghabi, K.A.
Annals of Microbiology, Vol.58, No.3, Year. 2008, Page: 555-560,
41.

Effect of dimethyl-β-cyclodextrin concentrations on the pulmonary delivery of recombinant human growth hormone dry powder in rats


Authors: Jalalipour, M., Najafabadi, A.R., Gilani, K., Esmaily, H., Tajerzadeh, H
Journal of Pharmaceutical Sciences, Vol.17, No.1, Year. 2008, Page:5176-5185,
42.

In vitro study of polyoxyethylene alkyl ether niosomes for delivery of insulin


Authors: Pardakhty, A., Varshosaz, J., Rouholamini, A.
International Journal of Pharmaceutics, Vol.328, No.2, Year. 2007,
43.

A Plackett-Burman design for screening of the operation variables in the formation of salbutamol sulphate particles by supercritical antisolvent


Authors: Vatanara, A., Rouholamini Najafabadi, A., Gilani, K., Asgharian, R., Darabi, M., Rafiee-Tehrani, M
Journal of Supercritical Fluids, Vol.40, No.1, Year. 2007, Page: 111-116,
44.

The effect of protein stabilizers on the physical state and aerosol performance of spray-dried albumin microparticles


Authors: Jalalipour, M., Rouholamini Najafabadi, A., Tajerzadeh, H., Gilani, K., Barghi, M.
Journal of Drug Delivery Science and Technology, Vol.17, No.2, Year. 2007, Page:149-153,
45.

Influence of mechanical milling time on physicochemical properties and stability of cefotaxime sodium


Authors: Rouholamini Najafabadi, A., Asgharian, R., Tajerzadeh, H., Gilani, K., Vatanara, A., Darabi, M.
Daru, Vol.15, No.1, Year. 2007, Page: 27-33,
46.

The effect of micronization method on characterization and deposition profiles of different dry powder formulations of cefotaxime sodium


Authors: Najafabadi, A.R., Asgharian, R., Tajerzadeh, H., Gilani, K., Vatanara, A., Darabi, M.
Journal of Drug Delivery Science and Technology, Vol.16, No.5, Year. 2006, Page:363-368,
47.

The effects of fine lactose as a third component on aerosolization of cefotaxime sodium from dry powder formulations


Authors: Najafabadi, A.R., Asgharian, R., Tajerzadeh, H., Gilani, K., Vatanara, A., Darabi, M.
Daru, Vol.14, No.3, Year. 2006, Page:155-163,
48.

Solubility of some inhaled glucocorticoids in supercritical carbon dioxide


Authors: Vatanara, A., Najafabadi, A.R., Khajeh, M., Yamini, Y
Journal of Supercritical Fluids, Vol.33, No.1, Year. 2005, Page:21-25,
49.

The effect of water to ethanol feed ratio on physical properties and aerosolization behavior of spray dried cromolyn sodium particles


Authors: Gilani, K., Rouholamini Najafabadi, A., Barghi, M., Rafiee-Tehrani, M.
Journal of Pharmaceutical Sciences, Vol.94, No.5, Year. 2005, Page:1048-1059,
50.

Formation of salbutamol sulphate microparticles using solution enhanced dispersion by supercritical carbon dioxide


Authors: Najafabadi, A.R., Vatanara, A., Gilani, K., Tehrani, M.R
Daru, Vol.13, No.1, Year. 2005, Page: 1-5,
51.

Intranasal bioavailability of insulin from carbopol-based gel spray in rabbits


Authors: Najafabadi, A.R., Moslemi, P., Tajerzadeh, H
Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents, Vol.11, No.5, Year. 2004, Page:295-300,
52.

Aerosolisation of beclomethasone dipropionate using spray dried lactose/polyethylene glycol carriers


Authors: Gilani, K., Rouholamini Najafabadi, A., Barghi, M., Rafiee-Tehrani, M
European Journal of Pharmaceutics and Biopharmaceutics, Vol.58, No.3, Year. 2004, Page:595-606,
53.

Influence of formulation variables and inhalation device on the deposition profiles of cromolyn sodium dry powder aerosols


Authors: Gilani, K., Najafabadi, A.R., Darabi, M., Barghi, M., Rafiee-Tehrani, M.
Daru, Vol.12, No.3, Year. 2004, Page: 123-130,
54.

The effect of vehicle on physical properties and aerosolisation behaviour of disodium cromoglycate microparticles spray dried alone or with L-leucine


Authors: Najafabadi, A.R., Gilani, K., Barghi, M., Rafiee-Tehrani, M.
International Journal of Pharmaceutics, Vol.285, No.1-2, Year. 2004, Page:97-108,
55.

A rapid and sensitive method for simultaneous determination of insulin and A21-desamido insulin by high-performance liquid chromatography


Authors: Moslemi, P., Najafabadi, A.R., Tajerzadeh, H.
Journal of Pharmaceutical and Biomedical Analysis, Vol.33, No.1, Year. 2003, Page:45-51,
56.

Development and Physical Characterization of Sorbitan Monoester Niosomes for Insulin Oral Delivery


Authors: Varshosaz, J., Pardakhty, A., Hajhashemi, V.-I., Najafabadi, A.R.
Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents, Vol.10, No.4, Year. 2003, Page:251-262,
57.

Desogm and evaluation of a new dry powder inhaler


Authors: Najafabadi, A.R., Gilani, K., Hozan, A.
Daru, Vol.9, No.3-4, Year. 2001, Page: 46-49,
58.

The effect of suspension concentration on aerosols produced by metered dose inhalers (MDIS)


Authors: Rouholamini Najafabadi, A., Ganderton, D.
Journal of Pharmacy and Pharmacology, Supplement, Vol.43, Year. 1991, Page:33,
59.

The effect of surfactant concentration on the size of aging droplets produced by a metered dose inhaler


Authors: Najafabadi, A.R., Ganderton, D
Journal of Pharmacy and Pharmacology, Supplement, Vol.42, Year. 1990, Page:12,
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