Tehran University of Medical Sciences
home | Farsi
Print

Esmaeil Sadroddiny

Contact Information
wwwbiotech-immunotech.blogspot.com
Tel: 00982143052000 داخلی 120 و 121
Fax: 00982188991117
Address: Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran,
Academic Rank
Associate Professor
School
Advanced Technologies in Medicine
Medical Biotechnology
About
CV last edited on: 2017/08/11

1.

B.Sc


Medical Laboratory Sciences, Iran University of Medical Sciences, Tehran, Iran, 2000
2.

M.Sc


Medical Biotechnology, Tarbiat Modares University, Tehran, Iran, 2004
Thesis Title:Preparation of anti-MUC1 recombinant antibody using phage display technology
Supervisor:Mohamad J Rasaee
3.

Ph.D


Medical Biotechnology , The University of Sheffield, Sheffield, United Kingdom, 2010
Thesis Title:A Proteomics approach to the study of the functional consequences of IgE-mediated activation of mast cells
Supervisor:Birgit A Helm
1.

English


Speaking: Good, Reading: Good, Writing: Good
1.

privileged associate professor of school of advanced technologies in medicine


2017,
2.

Full Ph.D scholarship and life expences of Tehran University of Medical Sciences


2007-2010 Sheffield University/UK,

Scientific Position

1.

Head of Medical Biotechnology Department


School of Advanced Technologies in Medicine, Tehran University of Medical Sciences , From October 2014
2.

Scientific consultant of Shifa pharmed industrial unit


Shifa pharmed, 2015-2016

Ph.D

1.

Research methodology


Ph.D.
2.

Genetic engineering


Ph.D.
3.

Nanobiotechnology


Ph.D.
4.

3D cell culture


Ph.D.
5.

Molecular cell biology


Ph.D.
1.

Scientific writing


Tehran University of Medical Sciences, 2012, سخنرانی, Lecturer
2.

Research methodology


Tehran University of Medical Sciences, 2012 سخنرانی, Lecturer
3.

3D Cell Culture


Tehran University, Faculty of New Sciences and Technologies, 2012 سخنرانی, Lecturer
4.

Recombinant antibody production using phage display technologies


Tarbiat Modares University, 2007 سخنرانی, Lecturer

Supervisor

1.

Molecular cloning of Bone Morphogenetic Protein-2 (BMP- 2) in pGEM-b1 vector and transformation into E.coli Rosetta strain


Zahra Sadri Najaf Abadi,
M.S,
2.

Expression and production of BMP-2 in Leishmania Tarentolae


Shabnam Razavi,
Ph.D,

Farsi

1.

بیوانفورماتیک پروتئینها


Authors: اسماعیل صدرالدینی
Publisher: رویان پژوه, 2016, 1, ترجمه
2.

کتاب جامع آزمون زبان کارشناسی ارشد


Authors: زیر نظر دکتر اسماعیل صدرالدینی
Publisher: رویان پژوه, 1394, Original
3.

سلولهاي بنيادي بالغ انسان


Authors: جعفر آي، اسماعيل صدرالديني
Publisher: جهاد دانشگاهي, 1392, ترجمه

Farsi

1.

کشت سه بعدی سلول


Authors: دکتر اسماعیل صدرالدینی
فارسی, Publisher: اننشارات تعالی اندیشه, 1392, 1, ترجمه

Papers

English

1.

Decorating and loading ghosts with allergens for allergen immunotherapy


Authors: Songwe Fanuel, Saeideh Tabesh, Huda Fatima Rajani, Sahel Heidari, Esmaeil Sadroddiny
Human Vaccines & Immunotherapeutics , Year. 2017,
2.

A novel recombinant anti-EGFR peptide vaccine capable of active immunization and reduction of tumor volume in mice model


Authors: Majid Asadi-Ghalehni1, Mohamad Javad Rasaee2, ...Esmaeil Sadroddiny,
Microbiology and immunology, Year. 2017,
3.

Machine learning and data mining techniques for medical complex data analysis


Authors: Hamid Alinejad-Rokny a, Esmaeil Sadroddiny b, Vinod Scaria c
Neurocomputing, Year. 2017,
4.

Analysis of predicted B and T-cell epitopes in Der p 23, allergen from Dermatophagoides pteronyssinus


Authors: Songwe Fanuel1, 2, Saeideh Tabesh3, Esmaeil Sadroddiny1, Gholam Ali Kardar1, 2*
Bioinformation, Year. 2017, Page:13(9): 307-312 ,
5.

Critical-sized full-thickness skin defect regeneration using ovine small


Authors: Morteza Rashtbar,1 Jamshid Hadjati,1,2 Jafar Ai,1 Sadegh Shirian,3,4 Issa Jahanzad,5
Journal of Biomedical Materials Research: Part B - Applied Biomaterials, Year. 2017,
6.

Decorating and Loading Ghosts with allergens for Allergen Immunotherapy


Authors: Songwe Fanuel, Saeideh Tabesh, Huda Fatima Rajani, Sahel Heidari, Esmaeil
Human Vaccines & Immunotherapeutics, Year. 2017,
7.

Construction of Genetically Engineered M13K07 Helper Phage for Simultaneous Phage Display of Gold Binding Peptide 1 and Nuclear Matrix Protein 22 ScFv Antibody


Authors: Farnaz Fatemi1, Sharmin Kharrazi2, Mohammad Amini2, Mohammad Javad Rasaee3, Mohammad Ali Mazlomi1, Majid Asadi-Ghalehni 1, Masoumeh Rajabibazl4* and Esmaeil Sadroddiny1*
Colloids and Surfaces B: Biointerfaces, Year. 2017,
8.

Comparative evaluation of probiotics effects on plasma glucose, lipid and insulin levels in streptozotocin-induced diabetic rats


Authors: Faeghe Memarrast1&, Soudeh Ghafouri-Fard2&, Sedighe Kolivand1, Saeedeh Jafary-Nodooshan1, Nadia Neyazi3, 4, Esmaeil Sadroddiny1, Elahe Motevaseli5, 6*
Diabetes/Metabolism Research and Reviews, Year. 13 June 2017,
9.

Characterization of decellularized ovine small intestine sub-mucosal layeras extracellular matrix based scaffold for tissue engineering


Authors: Morteza Rashtbar1, Jamshid Hadjati1,2, Jafar Ai1, Issa Jahanzad3, Mahmoud Azami1, Sadegh shirian4,5, Somayeh Ebrahimi-Barough1, Esmaeil Sadroddiny6
Journal of Biomedical Materials Research: Part B - Applied Biomaterials, Year. 2017,
10.

Expression of recombinant parvalbumin from wolf-herring fish and determination of its IgE-binding capability


Authors: Mohsen Mohammadi, Kobra Mokhtarian, Gholam Ali Kardar, Shokrollah Farrokhi, Esmaeil Sadroddiny, Mohammad Reza Khorramizadeh, and Reza Falak
Food and Agricultural Immunology, Year. 2017,
11.

Recellularization on Acellular Lung Tissue Scaffold Using Perfusion-Based Bioreactor: An Online Monitoring Strategy


Authors: Ali Doryab, Motaharehsadat Heydarian, Ghassem Amoabediny, Esmaeil Sadroddiny, Seyedhossein Mahfouzi
Journal of Medical and Biological Engineering, Year. 2017, Page:1-10,
12.

Lung cancer and miRNAs: a possible remedy for anti-metastatic, therapeutic and diagnostic applications


Authors: Zahra Sadat Hashemi, Saeed Khalili, Mehdi Forouzandeh Moghadam & Esmaeil Sadroddiny
Expert Review of Respiratory Medicine, Vol.11, No.2, Year. 2017,
13.

Improved human endometrial stem cells differentiation into functional hepatocyte-like cells on a glycosaminoglycan/collagen-grafted polyethersulfone nanofibrous scaffold


Authors: 1. Farzaneh Khademi1,2,3, Jafar Ai1,4,*, Masoud Soleimani3,5,*, Javad Verdi4, Seyed Mohammad Tavangar4,6, Esmaeil Sadroddiny7, Mohammad Massumi8 and Seyed Mahmoud Hashemi9
J of Biomedical materials research, Year. 2016,
14.

Identification and Characterization of Main Allergic Proteins in Cooked Wolf Herring Fish


Authors: Mohsen Mohamadi, Reza Falak, Kobra Mokhtarian, Mohammad Reza Khoramizadeh, Esmaeil Sadroddiny, Gholam Ali Kardar
Iranian Journal of Allergy, Asthma and Immunology , Vol.15, No.5, Year. 2016,
15.

Application of immuno-PCR assay for the detection of serum IgE specific to Bermuda


Authors: Rahmatpour S, Khan AH, Kalmarzi RN, Rajabibazl M, Tavoosidana, Elahe Motevaseli, Nosratollah Zargham, Sadroddiny Ei,
Molecular and Cellular Probes, Year. 2016,
16.

The Role of Stem Cells in the Treatment of Cerebral Palsy


Authors: Anahita Kiasatdolatabadi & Nasrin Lotfibakhshaiesh & Meysam Yazdankhah,Somayeh Ebrahimi-Barough & Mina Jafarabadi & Arman Ai,Esmaeil Sadroddiny & Jafar Ai
Molecular Neurobiology, Year. 2016, Page:1-10,
17.

Nano-structures mediated co-delivery of therapeutic agents for glioblastoma treatment


Authors: Basil Mujokoro | Mohsen Adabi | Esmaeil Sadroddiny | Mahdi Adabi | Masood Khosravani
Recent Materials Science and Engineering, Vol.69, No.1, Year. 2016, Page:1092–1102,
18.

Albumin-Based Biomaterial for Lungs Tissue Engineering Applications


Authors: Hammed T. Aiyelabegan, Sadaf S. Z. Zaidiab, Songwe Fanuel, Ali Eatemadi, Malihe T.K. Ebadi & Esmaeil Sadroddiny*
International Journal of Polymeric Materials and Polymeric Biomaterials, Year. 2016,
19.

Application of immuno-PCR for the detection of early stage cancer


Authors: Amjad Hayat Khan, Esmaeil Sadroddiny*
Molecular and Cellular Probes, Year. 2016,
20.

Cloning and expression of human bone morphogenetic protein-2 gene in leishmania tarentolae


Authors: Majid Rahmati1, Amjad Hayat Khan1,2, Shabnam Razavi1, Mohammad Reza khorramizadeh1, Mohammad Javad Rasaee3, Esmaeil Sadroddiny*1
Biocatalysis and Agricultural Biotechnology, Year. 2016,
21.

Inducible expression of indoleamine 2,3-dioxygenase attenuates acute rejection of tissue-engineered lung allografts in rats


Authors: Ebrahimi A1, Kardar GA2, Toolabi L3, Ghanbari H4, Sadroddiny E5.
Gene, Vol.576, No.1, Year. 2016, Page:412-420,
22.

Molecular Cloning of Bone Morphogenetic Protein-2 (BMP- 2) in pGEM-b1 Vector and Transformation into E.coli Rosetta Strain


Authors: Zahra Sadri Najaf Abadi 1, Farnaz Fatemi 1, Masoud Khosravani 2, Majid Rahmati 3, Esmaeil Sadroddiny 1*
International Journal of Health Studies, Vol.1, No.3, Year. 2015,
23.

In Silico and in vitro Evaluation of a Recombinant Fusion Peptide as a Novel Candidate Vaccine for EGFR-positive Tumors


Authors: Majid Asadi-Ghalehni1, Mohamad Javad Rasaee2, Masoud Khosravani3, Masoumeh Rajabi Bazl4, Mohsen Mohamadi1, Farnaz Fatemi1 and Esmaeil Sadroddiny*1
BIOSCIENCES BIOTECHNOLOGY RESEARCH ASIA, Vol.12, No.3, Year. 2015,
24.

Licensed monoclonal antibodies and associated challenges


Authors: Amjad Hayat Khan and Esmaeil Sadroddiny*
Human Antibodies, Vol.23, Year. 2015, Page:63–72,
25.

Decellularization of lung tissue and analysis of its differentiative potential on bone marrow mesenchymal stem cells of rat


Authors: Maesomeh tarahani nia, Akram Alizadeh, Ali Takhshid, Esmaeil Sadroddiny
J of Applied Tissue Engineering, Vol.2, No.1, Year. 2015,
26.

MicroRNAs in lung diseases: Recent findings and their pathophysiological implications


Authors: Ebrahimi A, Sadroddiny E.
Pulm Pharmacol Ther, Vol.34, Year. 2015, Page:55-63,
27.

COMPARATIVE STUDY OF INDOLAMINE 2, 3-DIOXYGENASE EXPRESSION IN ENDOMETRIAL AND BONE MARROW MESENCHYMAL STEM CELLS


Authors: LEILA EINI, KOBRA OMIDFAR, ESMAEIL SADRODDINY*, SHABNAM RAZAVI, NEGAR NAGHASH AND BAGHER LARIJANI
Journal of Biology and Nature, Vol.2, No.2, Year. 2015,
28.

Human endometrial stem cells differentiation into functional hepatocyte-like cells


Authors: Khademi F1, Soleimani M, Verdi J, Tavangar SM, Sadroddiny E, Masumi M, Ai J.
Cell Biology International, Year. 2014,
29.

Biomolecular markers in assessment and treatment of asthma


Authors: Farnaz Fatemi, Esmaeil Sadroddiny,*, Azam Gheibi, Taiebeh Mohammadi Farsani and Gholam Ali Kardar,
Respirology, Vol.19, No.4, Year. 2014, Page:514-523,
30.

Induced expression of indoleamine 2,3-dioxigenase in endometrial stem cells


Authors: Eini L, Sadroddiny E, Omidfar K, Sohrabi Hagh Doust I, Naghash N, Zare A.A
ABSTRACT: Cell Journal (YAKHTEH), Vol.14, No.1, Year. 2012, Page:34-34,
31.

The effects of TiO2 nanoparticles on inhibition and stimulation of MCF7 cells and human endometrial adult stem cells


Authors: Azadeh Hekmat, Ali Akbar Saboury and Esmaeil Sadroddiny
ABSTRACT: International Congress on Nanoscience & Nanotechnology, Year. 2012,
32.

Endometriosis and Endometrial stem cells


Authors: Jafar Ai and Esmaeil Sadroddiny
BOOK CHAPTER: Endometriosis, Year. 2012,
33.

Diagnostic and therapeutic applications of rat basophilic leukemia cells


Authors: Amir Rashid , Esmaeil Sadroddiny, Hong Tu Ye , Athanassios Vratimos , Sari Sabban , Eric Carey,Birgit Helm
Molecular Immunology, Vol.52, Year. 2012, Page:224-228,
34.

Protein Profilling at the secretome of RBL-2H3.1 cell line


Authors: E.Sadroddiny, J.Ai, A.K Pathak, T.K Pham, P.C Wright, B.A Helm
Iranian Journal of Immunology , Vol.9, No.1, Year. 2012, Page:1-31,
35.

A proteomics approach to study the molecular consequence of IgE-mediated cell signaling in RBL-2H3.1 cells and 2-D reference map preparation for RBL-2H3.1 cell line


Authors: Esmaeil Sadroddiny§, Arthur J.G Moir§, Birgit A. Helm§
Cell Biology International, Vol.35, Year. 2012,
36.

A novel insight to the functional role of Stathmin 1 in IgE-mediated activation of RBL-2H3 cells


Authors: Esmaeil Sadroddiny*, Arthur J.G Moir, Birgit A. Helm
Iranian J Allergy, Asthma and Immunology , Vol.10, No.2, Year. 2011, Page:73-80,
37.

A Proteomics approach to IgE-mediated antigen stimulation of mast cells


Authors: E. Sadroddiny, B.A Helm
ABSTRACT: THE FIRST BIOLOGY CONFERENCE FOR IRANIAN SCHOLARS IN EUROPE, Year. 2008,
38.

Production of Novel Recombinant Single-Domain Antibodies against Tandem Repeat Region of MUC1 Mucin


Authors: F.Rahbarizadeh,M.J.Rasaee,M.Forouzandeh Moghadam,A.A.Allameh and E.Sadroddiny
Hybridoma and hybridomics, Vol.23, No.3, Year. 2004, Page:151-153,
39.

Production of Single-Chain anti-MUC1 Antibody by DNA Chain Shuffling Method


Authors: E.Sadroddiny,M.J.Rasaee,M.Forouzandeh Moghadam, K.Omidfar, F.Rahbarizadeh, N.Golmakany
ABSTRACT: 7th IRANIAN CONGRESS OF IMMUNOLOGY AND AIIERGY MASHHAD , Year. 2004,
40.

Production of antibody against EGFR VIII and the other EGF receptor family and molecular cloning of heavy chain antibody receptoire of camelus bacterianus and camelus dromedarius


Authors: K.Omidfar,M.J.Rasaee,M.forouzandeh Moghadam, M.Taghikhani.H.Mojtahedi and E.Sadroddiny
FULL TEXT: 3th IRANIAN CONGRESS OF BIOTECHNOLOGY, Year. 2003,
41.

Induction of immune response and preparation of heavy-chain antibody cDNA library of Camelus bacterianus and Camelus dromedarius against MUC1


Authors: F.Rahbarizadeh,M.J.Rasaee. M.Forouzandeh Moghadam,A.A.Allameh and E.Sadroddiny
FULL TEXT: 3th IRANIAN CONGRESS OF BIOTECHNOLOGY, Year. 2003,
42.

Kinetic of cell growth and antibody production in rolling bottle


Authors: N.Golmakany, M.J Rasaee, M.Forouzandeh, A. Shojaosadati, S.Kashanian and E.Sadroddiny
FULL TEXT: 3th IRANIAN CONGRESS OF BIOTECHNOLOGY, Year. 2003,

Farsi

1.

بیان ایندول آمین 2و 3 دی اکسیژناز در سلولهای بنیادی مزانشیمی اندومتر تحت تیمار


Authors: لیلا عینی 1 ، نگار نقاش 1 ، باقر لاریجانی 2 ، جعفر آی 3 ، کیوان مجیدزاده 4 اسماعیل صدرالدینی 5  ، کبری امیدفر
مجله ديابت و متابوليسم ايران, Vol.2, No.13, Year. 1392, Page:153-162,
1.

Computational Biology, Biotechnology and machine learning


2015- Editorial Board Member,
1.

Cell culture


Bacterial, parasite and mammalian cell culture

2.

Methods in proteomics


Protein extraction, purification, separation and identification. Mass spectrometry, Post-translational modification analysis of proteins

3.

Methods in genomics


DNA and RNA extraction and purification, DNA manipulation and Genetic engineering techniques, Cloning and Expression analysis. Recombinant proteins and antibodies production.

4.

General techniques in medical laboratories


 Haematology, Biochemistry, Bacteriology, Immunology, Parasitology and Urinanalysis.

1.

European mast cell and basophil research network


Activity Type:عضو
2017
1.

Patent: Human albumin purification from fresh frozen plasma in fraction IV by modification of Cohn method


Date: 2017,
2.

Patent (82791): Lung Decellularization and recellularization using bioreactor


Date: 2014,
3.

Patent (80824): Bioreactor in lung tissue engineering


Date: 2013,
1. Antibody/Protein Biotechnology, Proteomics, (Stem) cell-based Immunomodulation

 Immune system could be considered as a two-edge blade that means it is beneficial as well as harmful while activated. Several disorders such as allergy, Asthma and autoimmune diseases would arise when immune responses get out of control. Also graft rejection still remains as a dilemma in transplantation and novel filed of medical sciences such as cell therapy and tissue engineering.

My back ground knowledge in biological sciences and personal interest lead me to orient my major researches on immune system in TWO POINTS OF VIEWFirst; (Stem)Cell-based Immunomodulation and the ways to control immune responses as a research point of view and Second; production, characterization and analysis of antibodies/proteins and proteomics as my technological point of view . Apparently, the protein molecules and antibodies which may involved in immune responses or treatment of immune system disorders would be my first choice research topics.  

Top