Tehran University of Medical Sciences
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Alireza Vatanara

Contact Information
Tel: 0098 21 66959057
Fax: 0098 21 66959057
Address: Aerosol Research Lab., Pharmaceutics Dept., School of Pharmacy,
Tehran University of Medical Sciences, Tehran, 14155-6451, Ir
Academic Rank
Assistant Professor
School
Pharmacy
Pharmaceutics
About
CV last edited on: 2015/17/03

1.

Ph.D


Pharmaceutics, Faculty of Pharmacy, Teheran University of Medical Sciences, Teheran, iran, 2005
2.

Pharm D


Pharmacy, Faculty of Pharmacy, Shahid Beheshti University of Medical Scien, Teheran, iran, 1998
1.

Arabic


Speaking: Good, Reading: Good, Writing: Good
2.

English


Speaking: Good, Reading: Good, Writing: Good
1.

Third prize winner (as colleague), 5th Iranian Scientific Razi Festival, Tehran


2003,

Supervisor

1.

Formulation and Processing of Infliximab DPI Using Spray Drying Technique and In vivo Evaluation of Its Anti Inflamatory Effects


Dr. H. Faghihi,
Ph.D, Pharmaceutics,
2.

Vaccination against Toxoplasma gondii infection by a combination of SAG1


M. Allahyari,
Ph.D, Pharmaceutical Biotechnology,
3.

Preparation and pharmacokinetic evaluation of dry powder inhalers containing sildenafil-PLGA nanoparticles


Dr. E. Ghasemian,
Ph.D, Pharmaceutics,
4.

Assessment of effects of formulation and processing parameters in thermostabilization of parenteral veterinary rabies vaccine vi


Dr. I. Vazirian,
Ph.D, Pharmaceutics,
5.

Formulation of parathyroid hormone using spray freeze drying process for dry powder inhalation


Dr. N. Poursina,
Ph.D, Pharmaceutics,
6.

Spray drying application in the particle engineering of monoclonal antibody and evaluation


Dr. V. Ramezani,
Ph.D, Pharmaceutics,
7.

Raloxifene loaded solid lipid nanoparticles (SLN): preparation and evaluation of oral bioavailability


Dr. M. Nabi Meibodi,
Ph.D, Pharmaceutics,
8.

Preparation and evaluation of Solid Lipid Nanoparticles Loaded by Cystein Proteinases Genes as a Novel Anti Leishmaniasis Vaccin


Dr. D. Doroud,
Ph.D, Pharmaceutics,
9.

Particle engineering of a model polymeric anticancer drug using supercritical fluids technology


Dr P. Kalantarian,
Ph.D, Pharmaceutics,

Advisor/Consulter

1.

Preparation and evaluation of inhalable microparticles containing


Dr. N. Mohajel,
Ph.D, Pharmaceutics,
2.

Preparation and evaluation of chitosan-based nanoparticles for rivastigmin delivery to brain via intranasal administration


Dr. H. Eftekhari,
Ph.D, Pharmaceutics,

Papers

English

1.

Formation of Polymeric Films Containing Supersaturated Contraceptive Drug by Transdermal Metered Dose Aerosol


Authors: Hoseini, F., Vatanara, A.*, Moazeni, E., Ahmadi, F., Darabi, M., Gilani, K., Rouhaolamini Najafabadi, A.
African Journal of Pharmacy and Pharmacology, Year. 2013,
2.

Effective Stabilization of Clarithromycin Aqueous Nanosuspensions Using Macromolecules


Authors: Esfandi, E., Ramezani, V., Vatanara*, A., Hadipoor, S.P., Najafabadi, A.R., Darabi, M., Nabi Meybodi, M.
Iranian Journal of Pharmaceutical Researches, Year. 2013,
3.

Improved brain delivery of vincristine using dextran sulfate complex solid lipid nanoparticles: Optimization and in vivo evaluation


Authors: Aboutaleb, E., Atyabi, F., Khoshayand, M.R., Vatanara, A., Ostad, S.N., Kobarfard, F., Dinarvand,R.
Journal of Biomedical Materials Research Part A, Year. 2013,
4.

Preparation, characterization and optimization of sildenafil citrate loaded PLGA nanoparticles by statistical factorial design


Authors: Ghasemian, E., Vatanara, A., Rouholamini Najafabadi, A., Rouini, M.R., Gilani, K., Darabi, M.
DARU, Journal of Pharmaceutical Sciences, Year. 2013,
5.

Solubility of megestrol acetate and levonorgestrel in supercritical carbon dioxide


Authors: Yamini, Y., Tayyebi, M., Moradi, M., Vatanara, A
Thermochimica Acta, Year. 2013,
6.

Optimization of supercritical carbon dioxide Extraction of essential oil from Pimpinella Affinis Ledeb. using Response Surface Methodology


Authors: Dashtianeh, M., Vatanara, A.*, Sefidkon, F., Fatemi*, S., Habibzadeh, M.
Journal of CO2 Utilization, Year. 2013,
7.

Effective Encapsulation of A Lipid and Water Insoluble Drug in Solid Lipid Nanoparticles Using A Modified Double Emulsion Solvent Evaporation Method


Authors: Nabi-Meibodi, M., Vatanara, A.*, Rouini,MR., Ramezani, V., Gilani, K.
Colloids and Surfaces B, Year. 2013,
8.

Measurement and correlation of the solubility of two steroid drugs in supercritical carbon dioxide using semi empirical models


Authors: Asiabi, H., Yamini, Y., Tayyebi, M., Moradi, M., Vatanara, A., Keshmiri, K.
Journal of Supercritical Fluids, Year. 2013,
9.

Optimization and physicochemical characterization of Baclofen-loaded Solid Lipid Nanoparticles


Authors: Nabi-Meibodi, M, Navidi, B., Navidi, N., Vatanara, A.*, Rouholamini Najafabadia, A., Ramezani, V.
Journal of Drug Delivery Sciences and Technology, Year. 2013,
10.

Development of a nano-micro carrier system for sustained pulmonary delivery of clarythromycin


Authors: Hadipour Moghaddam, S.P., Ramezani, V., Esfandi, E., Vatanara*, A., Darabi, M., Gilani, K., Najafabadi, A.R.
Powder Technology, Year. 2013,
11.

Effect of formulation ingredients on the physical characteristics of Salmeterol Xinafoate microparticles tailored by spray freeze drying


Authors: Rahmati, MR., Vatanara, A.*, Parsian, AR., Gilani, K., Malek Khosravi, K., Darabi, M., Rouholamini Najafabadi, A.
Advanced Powder Technology, Vol.24, Year. 2013, Page:36-42,
12.

Screening and evaluation of variables in the formation of antibody particles by spray drying


Authors: Ramezani, V., Vatanara, A., Rouholamini najafabadi, A., Gilani, K., Nabi-Meibodi, M.,
Powder Technology, Vol.223, No.1, Year. 2013, Page:341-346,
13.

Loading Hydrophilic Drug in Solid Lipid Media as Nanoparticles; Statistical Modeling of Entrapment Efficiency and Particle Size


Authors: Ghadiri M., Vatanara, A., Rouholamini Najafabadi, A., Fatemi, S.
International Journal of Pharmaceutics, Vol.424, No.1-2, Year. 2012, Page:128-137,
14.

Comparison of essential oil composition of Eucalyptus oleosa obtained by supercritical carbon dioxide and hydrodistillation


Authors: Gholivand, M.B., Rahimi-Nasrabadi, Vatanara, A., M., Niasari, M.
Journal of Herbs, Spices and Medicinal Plants, Year. 2012, Page:In Press,
15.

Screening and evaluation of variables in the formation of antibody particles by spray drying


Authors: Ramezani, V., Vatanara, A., Rouholamini najafabadi, A., Gilani, K., Nabi-Meibodi, M.
Powder Technology, Year. 2012, Page:In Press,
16.

Drying of a plasmid containing formulation: chitosan as a protecting agent


Authors:
DARU, J Pharm Sci, Year. 2012, Page:In Press,
17.

Effect of formulation ingredients on the physical characteristics of Salmeterol Xinafoate microparticles tailored by spray freeze drying


Authors: Rahmati, MR., Vatanara, A.*, Parsian, AR., Gilani, K., Malek Khosravi, K., Darabi, M., Rouholamini Najafabadi, A.,
Advanced Powder Technology, Year. 2012, Page:In Press,
18.

Process Variables in the Formation of Nanoparticles of Megestrol Acetate through Rapid Expansion of Supercritical CO2


Authors: Samei, M., Fatemi, S., Vatanara,A.*, Rouholamini Najafabadi, A.
Journal of Supercritical Fluids, Vol.70, Year. 2012, Page:1-7,
19.

Production of Ultrafine Drug Particles through Rapid Expansion of Supercritical Solution; A Statistical Approach


Authors: Pourasghar, M., Fatemi, S., Vatanara, A.*, Rouholamini Najafabadi, A.
Powder Technology, Vol.225, Year. 2012, Page:26-21,
20.

Comparative extraction of volatile oil components from Pimpinella affinis ledeb using supercritical CO2 and steam distillation


Authors: Dashtianeh, M., Fatemi, S., Vatanara, A., Sefidkon, F., Habibzadeh, M.
International Research Journal of Pharmacy and Pharmacolology, Vol.2, No.3, Year. 2012, Page:64-70,
21.

Optimization of a spray drying process to prepare dry powder microparticles containing plasmid nanocomplex


Authors: Mohajel, N., Roholamini Najafabadi, A., Azadmanesh, K., Vatanara, A., Moazeni, E., Rahimi, A., Gilani, K.,
International Journal of Pharmaceutics, Vol.423, No.2, Year. 2012, Page:577-585,
22.

Entrapment of 5-fluorouracil into PLGA matrices using supercritical antisolvent processes,


Authors: Kalantarian, P., Vatanara, A., Shokrgozar, M.A., Rouholamini Najafabadi, A., Haririan, I.,
Journal of Pharmacy and Pharmacology, Vol.63, Year. 2011, Page:500-506,
23.

Cysteine proteinase type I, encapsulated in Solid Lipid Nanoparticles induces substantial protection against L. major infection in C57BL/6 mice


Authors: Doroud, D, Zahedifard, F., Vatanara, A., Rouholamini Najafabadi, A., Rafati, S.
Parasite Immunology, Vol.33, No.6, Year. 2011, Page:335–348,
24.

Paromomycin Loaded Solid Lipid Nanoparticles: Characterization of Production Parameters


Authors: Ghadiri M., Vatanara, A., Rouholamini Najafabadi, A., Fatemi, S
Biotechnology and Bioprocess Engineering, Vol.16, Year. 2011, Page:617-623,
25.

Delivery of a cocktail DNA vaccine encoding cysteine proteinases type I, II and III with solid lipid nanoparticles potentiate protective immunity against Leishmania major infection


Authors: Doroud, D., Zahedifard, F., Vatanara, A., Rouholamini Najafabadi, A., Taslimi, Y., Vahabpour, R., Torkashvand, F., Vaziri, B., Rafati, S.
Journal of Controlled Release, Vol.153, No.2, Year. 2011, Page:154-162,
26.

C-terminal domain deletion enhances the protective activity of cpa/cpb loaded solid lipid nanoparticles against leishmania major in BALB/c mice


Authors: Doroud, D., Zahedifard, F., Vatanara, A., Taslimi, Y., Vahabpour, R., Torkashvand, F., Vaziri, B., Rouholamini Najafabadi, A., Rafati (2011) S
PLoS Neglected Tropical Diseases, Vol.5, No.7, Year. 2011, Page:1-16,
27.

Solubilities of Flutamide, Dutasteride and Finasteride as Antiandrogenic Agents, in Supercritical Carbon Dioxide:Measurement and Correlation


Authors: Yamini, Y., Kalantarian, P., Hojjati, M., Moradi, M., Vatanara, A., Harrian, I.
Journal of Chemical & Engineering Data, Vol.55, No.2, Year. 2010, Page:1056–1059,
29.

Chemical Composition of the Essential oil from Aerial Parts of Echinophora platyloba DC. from Iran


Authors: Rahimi-Nasrabadi, M., Gholivand, M.B., Niasari, M., Vatanara, A.
Journal of Medicinal Plants, Vol.9, Year. 2010, Page:53-56,
30.

Cationic Solid Lipid Nanoparticles Loaded by Cysteine Proteinase Genes as a Novel Anti-Leishmaniasis DNA Vaccine Delivery System: Characterization and In Vitro Evaluations


Authors: Doroud, D., Vatanara, A., Zahedifard, F., Gholami, E., Vahabpour, R., Rouholamini Najafabadi, A., Rafati, S
Journal of Pharmacy and Pharmaceutical Sciences, Vol.13, No.3, Year. 2010, Page:320 - 335,
31.

Supercritical Anti-solvent for Preparation of Anti-cancer Nanoparticles


Authors: Kalantarian, P., Rouholamini Najafabadi, A., Haririan, I., Vatanara, A., Yamini, Y., Darabi, M., Gilani, K.
International Journal of Nanomedicine, Vol.5, Year. 2010, Page:763-770,
32.

Precipitation of Fluticasone Propionate Microparticles Using Supercritical Antisolvent


Authors: Vatanara, A. Rouholamini Najafabadi, K. Gilani, R. Asgharian, M. Darabi, M. Rafiee – Tehrani
Vol.17, No.1, Year. 2009, Page:6-12,
33.

Supercritical CO2 and highly selective aromatase inhibitors : Experimental solubility and empirical data correlation


Authors: Hojjati, M., Vatanara, A., Yamini, Y., Moradi, M., Rouholamini Najafabadi, A
Journal of Supercritical Fluids, Vol.50, No.3, Year. 2009, Page:203-209,
34.

Enrichment of Omega3 fatty acids from Tyulka Oil by Supercritical CO2 Extraction,


Authors: Nei Nei, H., Fatemi, Sh., Salimi, A., Vatanara, A
Journal of Chemical Technology & Biotechnology, Vol.84, Year. 2009, Page:1854-1859,
35.

Chemical composition of the essential oil from leaves and flowering aerial parts of psammogeton canescens (DC) Vake from Iran


Authors: Rahimi-Nasrabadi, M., Gholivand, M. B., Batooli, H., Vatanara, A
Journal of Medicinal Plants, Vol.8, No.31, Year. 2009, Page:82-86,
36.

Comparison of super critical fluid extraction and hydrodistillation methods on Lavander's essential oil composition and yield.,


[link]
Authors: Rezazadeh, Sh., Baha-Aldini, B.Z.B.F., Vatanara, A., Behbahani, B., Rouholamini Najafabadi, A., Maleky-Doozzadeh, M., Yarigar-Ravesh, M., Pirali Hamedani, M.
Journal of Medicinal Plants, Vol.7, No.4, Year. 2008, Page:63-68,
37.

A Plackett–Burman design for screening of the operation variables in particle formation by supercritical antisolvent


Authors: Vatanara, A., Rouholamini Najafabadi, A., Gilani, K., Asgharian, R., Darabi, M., Rafiee Tehrani, M
Journal of Supercritical Fluid, Vol.40, No.1, Year. 2007, Page:111-116,
38.

Solubility of some statin drugs in supercritical carbon dioxide and representing the solute solubility data with several density-based correlations


Authors: Hojjati, M., Yamini,Y., Khajeh, M., Vatanara, A.
Journal of Supercritical Fluids, Vol.4, No.12, Year. 2007, Page:187-194,
39.

Influence of mechanical milling time on physicochemical properties and stability of cefotaxime sodium


Authors: Rouholamini Najafabadi A., Asgharian R., Tajerzadeh H., Gilani K., Vatanara A., Darabi M
Daru, Vol.15, No.1, Year. 2007, Page:27-33,
40.

Extraction and preconcentration of salbutamol and terbutaline from aqueous samples using hollow fiber supported liquid membrane containing anionic carrier


Authors: Yamini, Y., Reimann, C. T., Vatanara, A., and Jönsson, J. A.
Journal of Chromatography A, Vol.1124, No.1-2, Year. 2006, Page:57-67,
41.

The effect of micronization method on characterization and deposition profiles of different dry powder formulations of cefotaxime sodium


Authors: Rouholamini Najafabadi A., Asgharian R., Tajerzadeh H., Gilani K., Vatanara A., Darabi M.
Journal of Drug Delivery Sciences and Technology, Vol.16, No.5, Year. 2006, Page:363-368,
42.

The effects of fine lactose as a third component on aerosolization of cefotaxime sodium from dry powder formulations


Authors: Rouholamini Najafabadi A., Asgharian R., Tajerzadeh H., Gilani K., Vatanara A., Darabi M
Daru, Vol.14, No.3, Year. 2006, Page:155-163,
43.

Formation of salbutamol sulphate microparticles using solution enhanced dispersion by supercritical carbon dioxide


Authors: Rouholamini Najafabadi, A., Vatanara, A., Gilani, K., Rafiee Tehrani, M.
Daru, Vol.13, No.1, Year. 2005, Page:1-6,
44.

Solubility of some inhaled glucocorticoids in supercritical carbon dioxide


Authors: Vatanara, A., Rouholamini Najafabadi, A, Khajeh, M. and Yamini, Y
Journal of Supercritical Fluid, Vol.33, Year. 2005, Page:21-25,

Abstracts and Presentations

English

1.

The effect of L. Leusine and Ethanol on the properties of spray dried powders for inhalation


Location: Scotland,
Date: 2003-Type : Abstract, Journal: Controlled Release Society 30th Annual Meeting, Lecturer,
2.

Evaluation of cefotaxim sodium microparticles for respiratory drug delivery


Location: France,
Date: 2005-Type : Abstract, Journal: Respiratory Drug Delivery – Europe, Lecturer,
3.

Influence of process parameters on the formation of salbutamol sulphate particles using supercritical carbon dioxide


Location: England,
Date: 2004-Type : Abstract, Journal: Drug delivery to the lungs 15, Lecturer,
4.

Evaluation of the process conditions in the formation of fluticasone propionatemicroparticles by supercritical antisolvent


Location: Scotland,
Date: 2005-Type : Abstract, Journal: Drug delivery to the lungs 16, Lecturer,
5.

Extraction and preconcentration of Salbutamol and Terbutaline as doping drugs using hollow fibre supported liquid membrane cont


Location: UK,
Date: 2006-Type : Abstract, Journal: Extech , Lecturer,
6.

Pharmacological study on Lavender extracts prepared by hydrodistillation and supercritical extraction


10th Iranian Pharmaceutical Sciences Congress
Location: iran,
Date: 2006-Type : Abstract, Lecturer,
7.

Influence of Processing Methods on the Aerodynamic Behavior of Salbutamol Sulphate Micropaticles


The 3rd iranian conference of novel drug delivery systems
Location: iran,
Date: 2007-Type : Abstract, Lecturer,
8.

Second Generation of Colloidal Drug Carriers in Leishmaniasis Treatment


11th Iranian Pharmaceutical Sciences Conference
Location: iran,
Date: 2008-Type : Abstract, Lecturer,
9.

Nanoparticles of 5-FU for Inhalation Precipitated by Supercritical Carbon Dioxide


Location: Portugal,
Date: 2009-Type : Abstract, Journal: Respiratory Drug Delivery- Europe, Lecturer,
10.

Cationic solid lipid nanoparticles loaded by cystein proteinase genes as a novel anti leishmaniasis DNA vaccine delivery system


Location: Netherlands,
Date: 2010-Type : Abstract, Journal: , 11th European Symposium on Controlled Drug Delivery, Lecturer,
11.

Fluorouracil loaded poly (lactide co glycolide) injectable implants prepared by a supercritical antisolvent process


Location: USA,
Date: 2010-Type : Abstract, Journal: 37 th Annual Meeting & Exposition of the Controlled Release Society (CRS), , Lecturer,
12.

Enhanced transfection efficiency/cytotoxicity ratio of a novel leishmania DNA cocktail vaccine formulated with positively charge


14th International Congress of Immunology
Location: Japan,
2010Type : Abstract, Lecturer,
13.

Formulation of selected leishmania DNA vaccine candidates in solid lipid nanoparticles: characterization and in vitro evaluatio


10th International Congress of Immunology and Allergy of Iran
Location: iran,
Date: 2011-Type : Abstract, Lecturer,
14.

Formation of Porous Microparticles of Salmeterol Xinafoate Using Spray Freeze Drying (SFD)


Location: Germany,
Date: 2011-Type : Abstract, Journal: Respiratory Drug Delivery-Europe, Germany, Lecturer,
1.

DARU, J Pharm Sci


2008- Editor,
1.

Pharmaceutical processing by Supercritical Fluids


2.

Pharmaceutical Particle Engineering


1.

Member of Iranian Inventors Association (IIA).


Activity Type:Member
1. Pharmaceutical Particle Design - Micro & Nano
2. Biopharmaceutical Processing
3. Pulmonary and Nasal Drug Delivery
4. Supercritical Extraction of Pharmaceuticals and Medicinal Herbs
5. Solubility Study of Pharmaceuticals in Supercritical Carbon Dioxide
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