Tehran University of Medical Sciences
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Ahmad Ameri

Transconjunctival injection of botulinum toxin without electromyographic control in management of essential infantile esotropia

Authors: Dr.ameri,Dr.samarehie,Dr.ahadzadegan,Dr.anvari,Dr.jafari,Dr.yazdani
Journal of Current Ophthalmology, Vol.19, No.1, 2006,Page:84-87

Purpose: This study was designed to evaluate the efficacy of Botulinum toxin injection to the medial rectus muscles for management of essential infantile esotropia without electromyographic control.

Patients & Methods: Twenty four consecutive neurologically normal children from 8 to 38 months of age entered a case series with a mean deviation angle of 40 prism diopters. Simultaneous injection of 10 units Botulinum toxin A (Dysport) were made into the medial rectus muscles under halotane in halation anesthesia. Post operative controls were performed 3 days, 3 weeks, 3 months and 6 months after the injection.
Results: At 6 months, residual deviation was an average of 7.08 prism diopters of esotropia (25 prism diopters of esotropia to 10 prism diopters of exotropia).
Conclusion: Transconjuctival Botulinum toxin injection even without electromyographic assistance is an effective method in control of essential infantile esotropia in children.