Tehran University of Medical Sciences
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Ahmad Ameri

Botulinum toxin injection in the patients with Duane syndrome type 1

Authors: Ahmad Ameri, Farzad Farzbod , Fatemeh Bazvand, , Arash Mirmohammadsadeghi, Mohammadreza Akbari, Faramarz Anvari, Simindokht Hosseini
Keywords: Duane syndrome; Botulinum toxin; Esotropia
Journal of Current Ophthalmology, Vol.29, No.1, 2017,Page:50-53


To evaluate the efficacy of botulinum toxin injection in the patients with type 1 Duane syndrome and identify the predictive factors for success.


Sixteen patients with esotropic type 1 Duane syndrome without history of ocular surgery were selected for this interventional case series. The botulinum toxin was injected in the medial rectus of all patients. Visual acuity, dry refraction, cyclo-refraction, ocular motility, and amount of deviation were measured. Complete success, partial success, and failure were defined as residual deviation/face turn less than 8 prism diopters (PD)/5°, 8-20 PD/5-15°, and equal or greater than 20 PD/15°, respectively.